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Symbol
Name
ID

Pfn4
profilin family, member 4
MGI:1920121

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

reproductive system phenotype

abnormal sperm flagellum morphology

abnormal sperm connecting piece morphology

abnormal sperm midpiece morphology

abnormal sperm mitochondrial sheath morphology

coiled sperm flagellum

necrospermia

abnormal sperm head morphology

abnormal acrosome morphology

abnormal acrosome assembly

abnormal proacrosomal vesicle fusion

globozoospermia

abnormal sperm nucleus morphology

small sperm head

abnormal spermatid morphology

abnormal manchette morphology

abnormal manchette assembly

absent manchette

decreased sperm progressive motility

asthenozoospermia

abnormal testis physiology

abnormal spermiogenesis

male infertility

impaired acrosome reaction

impaired fertilization

Availability

Mouse Genotype

Pfn4^em1Hsc/Pfn4^em1Hsc

*

Pfn4^em2Hsc/Pfn4^em2Hsc

*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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